>NC_002645_HCoV-229E_inf-1_nsp16_19666..20568_903bp_300aa
-SAEWKCGYSMPGIYKTQRMCLEPCNLYNYGAGLKLPSGIMFNVVKYTQLCQYFNSTTLC
VPHNMRVLHLGAGSDYGVAPGTAVLKRWLPHDAIVVDNDVVDYVSDADFSVTGDCATVYL
EDKFDLLISDMY---DGRTKAIDG-ENVSKEGFFTYINGFICEKLAIGGSIAIKVTEYSW
NKKLYELVQRFSFWTMFCTSVNTSSSEAFVVGINYLGDFAQGPFIDGNIIHANYVFWRNS
TVMSLSYNSVLDLSKFNCKHKATVVVQLKDSDINEMVLSLVRSGKLLVRGNGKCLSFSNH
LVSTK---------
>NC_005831_HCoV-NL63_AmsterdamI_nsp16_19573..20475_903bp_300aa
-SAEWKCGYAMPQIYKLQRMCLEPCNLYNYGAGIKLPSGIMLNVVKYTQLCQYLNSTTMC
VPHNMRVLHYGAGSDKGVAPGTTVLKRWLPPDAIIIDNDINDYVSDADFSITGDCATVYL
EDKFDLLISDMY---DGRIKFCDG-ENVSKDGFFTYLNGVIREKLAIGGSVAIKITEYSW
NKYLYELIQRFAFWTLFCTSVNTSSSEAFLIGINYLGDFIQGPFIAGNTVHANYIFWRNS
TIMSLSYNSVLDLSKFECKHKATVVVTLKDSDVNDMVLSLIKSGRLLLRNNGRFGGFSNH
LVSTK---------
>NC_002306_TGEV_PUR46-MAD_nsp16_19466..20368_903bp_300aa
-SAEWNPGYSMPTLYKIQRMCLERCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLC
VPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYI
EDKFDLLVSDLY---DGSTKSIDG-ENTSKDGFFTYINGFIKEKLSLGGSVAIKITEFSW
NKDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNS
TIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNH
FVNTP---------
>NC_003436_PEDV_CV777_nsp16_19736..20641_906bp_301aa
-ASEWKCGYSMPSIYKIQRMCLEPCNLYNYGAGVKLPDGIMFNVVKYTQLCQYLNSTTMC
VPHHMRVLHLGAGSDKGVAPGTAVLRRWLPLDAIIVDNDSVDYVSDADYSVTGDCSTLYL
SDKFDLVISDMY---DGKIKSCDG-ENVSKEGFFPYINGVITEKLALGGTVAIKVTEFSW
NKKLYELIQKFEYWTMFCTSVNTSSSEAFLIGVHYLGDFASGAVIDGNTMHANYIFWRNS
TIMTMSYNSVLDLSKFNCKHKATVVVNLKDSSISDVVLGLLKNGKLLVRNNDAICGFSNH
LVNVNK--------
>DQ811787_PRCV_ISU-1_nsp16_19446..20348_903bp_300aa
-SAEWYPGYSMPTLYKIQRMCLERCNLYNYGAQVKLPDGITTNVVKYTQLCQYLNTTTLC
VPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYI
EDKFDLLVSDLY---DGSTKSIDG-ENTSKDGFFTYINGFIKEKLSLGGSVAIKITEFSW
NKDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNS
TIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVIGLLRKGKLLIRNNGKLLNFGNH
FVNTP---------
>AY994055_FIPV_79-1146_nsp16_19537..20439_903bp_300aa
-SAEWNPGYSMPTLYKIQRMCLERCNLYNYGAQVRLPDGITTNVVKYTQLCQYLNTTTVC
VPHKMRVLHLGAAGASGVAPGSTVLRRWLPDDAILVDNDLRDYVSDADFSVTGDCTSLYI
EDKFDLLISDLY---DGSTKSIDG-ENTSKDGFFTYINGFIKEKLSLGGSAAIKITEFSW
NKDLYELIQRFEYWTVFCTSVNTSSSEGFLIGINYLGPYCDKAIVDGNIMHANYIFWRNS
TIMALSHNSVLDTPKFKCRCNNALIVNLKEKELNEMVVGLLRKGKLLIRNNGKLLNFGNH
LVNVP---------
>NC_009657_BtCoV-G1_BtCoV/512/2005_nsp16_19769..20674_906bp_301aa
-SAEWKCGYSMPSIYKIQRMCLEPCNLYNYGSGLKLPDGIMFNVVKYTQLCQYLNSTTMC
VPHHMRVLHLGAGSDKGVAPGTAVLRRWLPLDAVIVDNDVNDYVSDADFSYTGDCASMYL
TDKFDLVISDMY---DGRTKSCDG-DNVSKEGFFPYINGVITEKLALGGTVAIKITEFSW
NKKLYELIQKFEYWTLFCTSVNTSSSEAFLIGVHFLGDFSTNAIIDGNIMHANYIFWRNS
TIMTMSYNSVLDLSKFSCKHKATVVVNLKDSSVTDLVLGLLKNGKLLIRNNGVVCGFSNH
LVNSTK--------
>EF203064_Bat-CoV-HKU2_HKU2/GD/430/2006_nsp16_19577..20479_903bp_300aa
-SAEWKCGYSMPSLYKIQNMCMDACNLYNYGASIKLPDGIMFNVVKYTQLCQFLNTTTMC
VPHNMRVLHLGAGSDKGVAPGTAVLRRWLPDDAIIVDNDVNDYVSDADFSITGDCTHVYV
EDKFDLLISDMY---DGKIKSIDG-DNVSKDGFFTYINGFIREKLALGGAMAVKITEYSW
NKQLYEIAQKFEYWTLFCTSVNTSSSEAFLIGINYLGDFSSASVIDGNVMHANYIFWRNS
TIMTMSYNSVLDLSKFRCKHKATVIITLKDKDITDMVLGLIKNGKLLIRNSQKLLNFSNH
LVTTK---------
>NC_005147_HCoV-OC43_OC43_nsp16_20598..21497_900bp_299aa
AASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLA
VPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPF
DCQWDLIISDMY---DPITKNIGE-YNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSW
NAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLCK--PKVEIDGNVMHANYLFWRNS
TVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLIRDTNKEVFVGDS
LVNVI---------
>NC_006577_CoV-HKU1A_N1_nsp16_20854..21753_900bp_299aa
ATNDWKPGYSMPVLYKYLNVPLERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLA
VPVNMRVLHLGAGSDKEVAPGSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPF
DCHWDLIISDMY---DPLTKNIGD-YNVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSW
NADLYKLMSCFAFWTVFCTNVNASSSEGFLIGINYLGK--SSFEIDGNVMHANYLFWRNS
TTWNGGAYSLFDMTKFSLKLAGTAVVNLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDS
LVNTC---------
>AY884001_CoV-HKU1B_N2_nsp16_20758..21657_900bp_299aa
ATSDWKPGYSMPVLYKYLNVPLERVSLWNYGKAINLPTGCMMNVAKYTQLCQYLNTTTLA
VPVNMRVLHLGAGSDKEVAPGSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPF
DCHWDLIISDMY---DPLTKNIGD-YNVSKDGFFTYICYLIRDKLSLGGSVAIKITEFSW
NADLYKLMSYFAFWTVFCTNVNASSSEGFLIGINYLGK--SCFEIDGNVMHANYLFWRNS
TTWNGGAYSLFDMSKFSLKLAGTAVVNLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDS
LVNTC---------
>DQ339101_CoV-HKU1C_N5_nsp16_20698..21597_900bp_299aa
ATNDWKPGYSMPVLYKYLNVPLERVSLWNYGKPINLPTGCMMNVAKYTQLCQYLNTTTLA
VPVNMRVLHLGAGSDKEVAPGSAVLRQWLPSGSILVDNDLNPFVSDSLVTYFGDCMTLPF
DCHWDLIISDMY---DPLTKNIGD-YNVSKDGFFTYICHLIRDKLSLGGSVAIKITEFSW
NADLYKLMSCFAFWTVFCTNVNASSSEGFLIGINYLGK--SSFEIDGNVMHANYLFWRNS
TTWNGGAYSLFDMTKFSLKLAGTAVVNLRPDQLNDLVYSLIERGKLLVRDTRKEIFVGDS
LVNTC---------
>NC_003045_BCoV_BCoV-ENT_nsp16_20595..21494_900bp_299aa
AASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLA
VPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPF
DCQWDLIISDMY---DPITKNIGE-YNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSW
NAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGK--PKVEIDGNVMHANYLFWRNS
TVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDS
LVNVI---------
>NC_001846_MHV_MHV-A59_nsp16_20846..21745_900bp_299aa
AAADWKPGYVMPVLYKYLESPLERVNLWNYGKPITLPTGCMMNVAKYTQLCQYLSTTTLA
VPANMRVLHLGAGSDKGVAPGSAVLRQWLPAGSILVDNDVNPFVSDSVASYYGNCITLPF
DCQWDLIISDMY---DPLTKNIGE-YNVSKDGFFTYLCHLIRDKLALGGSVAIKITEFSW
NAELYSLMGKFAFWTIFCTNVNASSSEGFLIGINWLNK--TRTEIDGKTMHANYLFWRNS
TMWNGGAYSLFDMSKFPLKAAGTAVVSLKPDQINDLVLSLIEKGKLLVRDTRKEVFVGDS
LVNVK---------
>NC_007732_PHEV_VW572_nsp16_20598..21497_900bp_299aa
AASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLA
VPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPF
DCQWDLIISDMY---DPITKNIGE-YNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSW
NAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGK--SKVDIDGNVMHANYLFWRNS
TVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLIRDTNKEVFVGDS
LVNVI---------
>EF424621_AntelopeCoV_US/OH1/2003WD1418_nsp16_20580..21479_900bp_299aa
AASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLA
VPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPF
DCQWDLIISDMY---DPITKNIGE-YNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSW
NAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGK--PKVEIDGNVMHANYLFWRNS
TVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDS
LVNVI---------
>EF424622_GiCoV_US/OH3-TC/2006_nsp16_20579..21478_900bp_299aa
AASDWKPGYSMPVLYKYLNSPMERVSLWNYGKPVTLPTGCMMNVAKYTQLCQYLNTTTLA
VPVNMRVLHLGAGSEKGVAPGSAVLRQWLPAGTILVDNDLYPFVSDSVATYFGDCITLPF
DCQWDLIISDMY---DPITKNIGE-YNVSKDGFFTYICHMIRDKLALGGSVAIKITEFSW
NAELYKLMGYFAFWTVFCTNANASSSEGFLIGINYLGK--PKVEIDGNVMHANYLFWRNS
TVWNGGAYSLFDMAKFPLKLAGTAVINLRADQINDMVYSLLEKGKLLVRDTNKEVFVGDS
LVNVI---------
>NC_004718_SARS-human_Tor2_nsp16_20589..21485_897bp_298aa
ASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLA
VPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHT
ANKWDLIISDMY---DPRTKHVTK-ENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSW
NADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNT
NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDI
LVNN----------
>AY304488_SARS-civet_SZ16_nsp16_20574..21470_897bp_298aa
ASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLA
VPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHT
ANKWDLIISDMY---DPKTKHVTK-ENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSW
NADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNT
NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDI
LVNN----------
>NC_009694_SARS-bat_HKU3-1_nsp16_20568..21464_897bp_298aa
ASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLA
VPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHT
ANKWDLIISDMY---DPKTKHVLK-DNDSKEGFFTYLCGFIKQKLALGGSVAVKITEHSW
NADLYKLMGHFSWWTAFVTNVNASSSEAFLIGVNYLGK--PKEQIDGYTMHANYIFWRNT
NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDI
LVNN----------
>AY545919_SARS-badger_CFB/SZ/94/03_nsp16_20568..21464_897bp_298aa
ASQAWQPGVAMPNLYKMQRMLLEKCDLQNYGENAVIPKGIMMNVAKYTQLCQYLNTLTLA
VPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHT
ANKWDLIISDMY---DPRTKHVTK-ENDSKEGFFTYLCGFIKQKLALGGSIAVKITEHSW
NADLYKLMGHFSWWTAFVTNVNASSSEAFLIGANYLGK--PKEQIDGYTMHANYIFWRNT
NPIQLSSYSLFDMSKFPLKLRGTAVMSLKENQINDMIYSLLEKGRLIIRENNRVVVSSDI
LVNN----------
>NC_009019_Bat-CoV-HKU4_B04f HKU41_nsp16_20717..21625_909bp_302aa
ATNDWKPGLTMPSLFKVQQMNLEPCLLANYKQSIPMPNGVHMNVAKYMQLCQYLNTCTLA
VPANMRVIHFGAGCEKGVAPGTSVLRQWLPLDAVLIDNDLNEFVSDADITIFGDCVTVHV
GQQVDLLISDMY---DPCTKAVGE-VNQTKALFFVYLCNFIKNNLALGGSVAIKITEHSW
SADLYKIMGRFAYWTVFCTNANASSSEGFLIGINFLGE--LKEEIDGNVMHANYIFWRNS
TPMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKLLIRDNDTLNVSTDV
LVNFRKRL------
>NC_009020_Bat-CoV-HKU5_LMH3f HKU51_nsp16_20882..21808_927bp_308aa
AINDWKPGLAMPSLFKVQNSNLEPCMLPNYKQSIPMPQGVHMNIAKYMQLCQYLNTCTIA
VPANMRVMHFGAGSDKGVAPGSSVLRQWLPTDAILIDNDLNEYVSDADITLFGDCVTVRV
GQQVDLLISDMY---DPSTKVVGE-TNEAKALFFVYLCNFIKNNLALGGSVAIKITEHSW
SAELYELMGRFAWWTVFCTNANASSSEGFLIGINYLGE--LKEVIDGNVMHANYIFWRNT
TLMNLSTYSLFDLSRFPLKLKGTPVLQLKESQINELVISLLSQGKLIIRDNDTLSVSTDV
LVNFYRKPHKRSKC
>NC_009021_Bat-CoV-HKU9_BF_005I HKU91_nsp16_20127..21020_894bp_297aa
AKQDWKPGYSMPALYKVQNAVLEPCLLHNYGQAARLPSGTLMNVAKYTQLCQYLNTCSLA
VPAKMRVMHFGAGSDKGVCPGTAVLKQWLPADAYLVDNDLCYCASDADSTYVGSCETFFS
VNKWDFIFSDMY---DARTKNTSG-DNTSKEGFFTYLTGFIRSKLALGGSIAIKITEHSW
SADLYAIMGHFNWWTCFCTSVNSSSSEAFLIGVNYIG---VGALLDGWQMHANYVFWRNS
TVMQLSSYSLYDLQRFPLRLKGTPVMSLKEDQLNELVLNLIRAGRLIVRDAVDIGVRGVA
CSGV----------
>NC_001451_IBV_Beaudette_nsp16_19509..20417_909bp_302aa
--SAWTCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGILMNVAKYTQLCQYLSKTTIC
VPHNMRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYNT
EHKFDLVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSW
HEVLYDIAQDCAWWTMFCTAVNASSSEAFLIGVNYLGA-SEKVKVSGKTLHANYIFWRNC
NYLQTSAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDS
FVCTM---------
>AY646283_IBV-partridge_Partridge/GD/S14/2003_nsp16_19341..20249_909bp_302aa
--SAWTCGYNMPELYKVQNCVMEPCNIPNYGVGITLPSGIMMNVAKYTQLCQYLSKTTMC
VPHNMRVMHFGAGSDKGVAPGSTVLKQWLPEGTLIVDNDIVDYVSDAHVSVLSDCNKYKT
EHKFDLVISDMYTDNDSKRKHEGIVANNGNDDVFIYLSNFLSNNLALGGSFAIKVTETSW
HESLYEVAQDCAWWTLFCTAVNASSSEAFLVGINYLGA-SDKVKVSGKTLHANYIFWRNC
NYLQTSAYSAFDVAKFGLKLKATPVVNLKKEQKTDLVSNLLKNGKLLIRDVGEVTVFSDH
FVCTM---------
>AY641576_IBV-peafowl_Peafowl/GD/KQ6/2003_nsp16_19452..20360_909bp_302aa
--SAWTCGYNMPELYKVQNCVMEPCNIPNYGVGIALPSGIMMNVAKYTQLCQYLSKTTMC
VPHNMRVMHFGAGSDKGVAPGSTVLKQWLPEGTLLVDNDIVDYVSDAHVSVLSDCNKYKT
EHKFDLVISDMYTDNDSKRKHEGVIANNGNDDVFIYLSSFLRNNLALGGSFAVKVTETSW
HEVLYDIAQDCAWWTMFCTAVNASSSEAFLVGVNYLGA-SEKVKVSGKTLHANYIFWRNC
NYLQTSAYSIFDVAKFDLRLKATPVVNLKTEQKTDLVFNLIKCGKLLVRDVGNTSFTSDS
FVCTM---------